Flexcell® Culture Systems
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Flexcell® Tension Plus System

A computer-regulated bioreactor that uses vacuum pressure to apply cyclic or static strain to cells cultured on flexible-bottomed culture plates.


FX-4000T

View tension baseplate set up

Features:
  • Analyze biochemical changes in response to strain in cells from muscle, lung, heart, vascular vessels, skin, tendon, ligament, cartilage, and bone.
  • Uses vacuum pressure to deform a flexible-bottomed culture plate yielding up to 30% substrate elongation.
  • Applies a defined, controlled, static or cyclic deformation to cells growing in vitro.
  • Compatible with Windows Vista.
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Flexcell® Compression Plus System

A computer-regulated bioreactor that uses positive air pressure to deform tissue samples or 3-D cell cultures in vitro, simulating biological compression conditions.


FX-4000C

View compression baseplate set up

Features:
  • Uses positive pressure to compress samples between a piston and stationary platen on the BioPress culture plate yielding up to 14 lbs of force.
  • Program multiple frequency, amplitude, and wave changes in one regimen with defined, static or cyclic deformation of cells.
  • Valving mechanism regulates pressure to provide specified compression regimen.
  • Compatible with Windows Vista.
Product Catalog:

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Flexcell® FlexLink® Tension or Compression Plus System

A remote tesnion or compression unit that works in conjunction with the FX-4000T and/or FX-4000C allowing the user to simultaneously run two different regimens on two different baseplates.


FlexLink®

Features:
  • Can perform all of the functions of the FX-4000T and FX-4000C systems (depending on FlexLink® model purchased).
  • Four FlexLinks® can be connected in series to the central controller.
Product Catalog:

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Flexcell® Tissue Train® Culture System

A computer-regulated bioreactor that allows users to create 3-dimensional cell-seeded gels and apply uniaxial tensile strains to these gels.


Tissue Train®

View bioartificial tissue stretching with Tissue Train®

View Tissue Train® Gels

Features:
  • 3-D culture in a gel matrix with or without cyclic tension.
  • Build bioartificial tissue strips of skin, tendon, ligament, etc. up to 35 mm in length.
  • Observe responses of cells cultured in 3-D matrices with phase contrast, fluorescent, or scanning confocal microscopy.
  • Compatible with Windows Vista.
Product Catalog:

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Relevant Publications:

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Flexcell® StageFlexer® Jr. (Microscopy)

A new compact strain device designed to accept membranes removed from the well of a BioFlex®, Tissue Train®, or UniFlex® culture plate and observe signaling responses to strain in real time.


StageFlexer® Jr.

Features:
  • StageFlexer® Jr. consists of a single one inch well designed to accept a membrane removed from the BioFlex®, Tissue Train®, or UniFlex® plate.
  • The user can continue to manipulate cells while observing them in real time with a microscope.
  • The membrane can be deformed using the Flexcell® Tension Plus system.
Product Catalog:

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Flexcell® StageFlexer® (Microscopy)

A single-well embodiment of the BioFlex® culture plate designed to allow the user to observe signaling responses to strain in real time on a microscope stage.


StageFlexer®

Features:
  • Applies strain to cells in real time on your microscope stage.
  • Consists of a single 35 mm well with a matrix bonded silicone rubber membrane, similar to the membrane in the BioFlex® culture plates.
  • The membrane can be deformed using the Flexcell® Tension Plus system.
Product Catalog:

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Relevant Publications:

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Flexcell® StagePresser (Microscopy)

A single-well embodiment of the Compression Plus apparatus designed to allow the user to detect signaling responses to compression.


StagePresser

Features:
  • Designed to work with the FX-4000C system.
  • Requires a standard (upright) microscope and a light source that will illuminate the sample from above.
  • Produces real time results on your microscope stage.
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