Agarwal S, Deschner J, Long P, Verma A, Hofman C, Evans CH, Piesco N. Role of NF-kappaB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals. Arthritis Rheum 50(11):3541-3548, 2004.
Al-Sabah A, Stadnik P, Gilbert SJ, Duance VC, Blain EJ. Importance of reference gene selection for articular cartilage mechanobiology studies. Osteoarthritis Cartilage 24(4):719-30, 2016.
Beckmann R, Houben A, Tohidnezhad M, Kweider N, Fragoulis A, Wruck CJ, Brandenburg LO, Hermanns-Sachweh B, Goldring MB, Pufe T, Jahr H. Mechanical forces induce changes in VEGF and VEGFR-1/sFlt-1 expression in human chondrocytes. Int J Mol Sci 15(9):15456-74, 2014.
Bleuel J, Zaucke F, Brüggemann GP, Niehoff A. Effects of cyclic tensile strain on chondrocyte metabolism: a systematic review. PLoS One 10(3):e0119816, 2015.
Carvalho RS, Yen EH, Suga DM. Glycosaminoglycan synthesis in the rat articular disk in response to mechanical stress. American Journal of Orthodontics & Dentofacial Orthopedics 107(4):401-410, 1995.
Chen C, Wei X, Lv Z, Sun X, Wang S, Zhang Y, Jiao Q, Wang X, Li Y, Wei L. Cyclic equibiaxial tensile strain alters gene expression of chondrocytes via histone deacetylase 4 shuttling. PLoS One 11(5):e0154951, 2016.
Chen K, Yan Y, Li C, Yuan J, Wang F, Huang P, Qian N, Qi J, Zhou H, Zhou Q, Deng L, He C, Guo L. Increased 15-lipoxygenase-1 expression in chondrocytes contributes to the pathogenesis of osteoarthritis. Cell Death Dis 8(10):e3109, 2017. doi: 10.1038/cddis.2017.511.
Doi H, Nishida K, Yorimitsu M, Komiyama T, Kadota Y, Tetsunaga T, Yoshida A, Kubota S, Takigawa M, Ozaki T. Interleukin-4 downregulates the cyclic tensile stress-induced matrix metalloproteinases-13 and cathepsin B expression by rat normal chondrocytes. Acta Med Okayama 62(2):119-126, 2008.
Dossumbekova A, Anghelina M, Madhavan S, He L, Quan N, Knobloch T, Agarwal S. Biomechanical signals inhibit IKK activity to attenuate NF-B transcriptional activity in inflamed chondrocytes. Arthritis Rheum 56(10):3284–3296, 2007.
Fujisawa T, Hattori T, Takahashi K, Kuboki T, Yamashita A, Takigawa M. Cyclic mechanical stress induces extracellular matrix degradation in cultured chondrocytes via gene expression of matrix metalloproteinases and interleukin-1. J Biochem 125(5):966-975, 1999.
Fukuda K, Asada S, Kumano F, Saitoh M, Otani K, Tanaka S. Cyclic tensile stretch on bovine articular chondrocytes inhibits protein kinase C activity. Journal of Laboratory and Clinical Medicine 130(2):209-215, 1997.
Gassner R, Buckley MJ, Georgescu H, Studer R, Stefanovich-Racic M, Piesco NP, Evans CH, Agarwal S. Cyclic tensile stress exerts antiinflammatory actions on chondrocytes by inhibiting inducible nitric oxide synthase. The Journal of Immunology 163:2187–2192, 1999.
Gassner R, Buckley MJ, Piesco N, Evans C, Agarwal S. Cytokine-induced nitric oxide production of joint cartilage cells in continuous passive movement. Anti-inflammatory effect of continuous passive movement on chondrocytes: in vitro study. Mund Kiefer Gesichtschir 4(Suppl 2):S479-S484, 2000.
Gassner RJ, Buckley MJ, Studer RK, Evans CH, Agarwal S. Interaction of strain and interleukin-1 in articular cartilage: effects on proteoglycan synthesis in chondrocytes. International Journal of Oral & Maxillofacial Surgery 29(5):389-394, 2000.
Hdud IM, Mobasheri A, Loughna PT. Effects of cyclic equibiaxial mechanical stretch on α-BK and TRPV4 expression in equine chondrocytes. Springerplus 3:59, 2014.
Holmvall K, Camper L, Johansson S, Kimura JH, Lundgren-Akerlund E. Chondrocyte and chondrosarcoma cell integrins with affinity for collagen type II and their response to mechanical stress. Exp Cell Res 221(2):496-503, 1995.
Honda K, Ohno S, Tanimoto K, Ijuin C, Tanaka N, Doi T, Kato Y, Tanne K. The effects of high magnitude cyclic tensile load on cartilage matrix metabolism in cultured chondrocytes. Eur J Cell Biol 79(9):601-609, 2000.
Huang J, Ballou LR, Hasty KA. Cyclic equibiaxial tensile strain induces both anabolic and catabolic responses in articular chondrocytes. Gene 404:101–109, 2007.
Limoto S, Watanabe S, Takahashi T, Shimizu A, Yamamoto H. The influence of Celecoxib on matrix synthesis by chondrocytes under mechanical stress in vitro. Int J Mol Med 16(6):1083-1088, 2005.
Kawakita K, Nishiyama T, Fujishiro T, Hayashi S, Kanzaki N, Hashimoto S, Takebe K, Iwasa K, Sakata S, Nishida K, Kuroda R, Kurosaka M. Akt phosphorylation in human chondrocytes is regulated by p53R2 in response to mechanical stress. Osteoarthritis Cartilage 20(12):1603-9, 2012.
Lahiji K, Polotsky A, Hungerford DS, Frondoza CG. Cyclic strain stimulates proliferative capacity, 2 and 5 integrin, gene marker expression by human articular chondrocytes propagated on flexible silicone membranes. In Vitro Cell Dev Biol Anim 40(5-6):138-142, 2004.
Liu Q, Hu X, Zhang X, Dai L, Duan X, Zhou C, Ao Y. The TMSB4 pseudogene LncRNA functions as a competing endogenous RNA to promote cartilage degradation in human osteoarthritis. Mol Ther 24(10):1726-1733, 2016.
Liu Q, Hu X, Zhang X, Duan X, Yang P, Zhao F, Ao Y. Effects of mechanical stress on chondrocyte phenotype and chondrocyte extracellular matrix expression. Sci Rep 6:37268, 2016.
Liu Q, Zhang X, Hu X, Yuan L, Cheng J, Jiang Y, Ao Y. Emerging roles of circRNA related to the mechanical stress in human cartilage degradation of osteoarthritis. Mol Ther Nucleic Acids 7:223-230, 2017.
Long P, Gassner R, Agarwal S. Tumor necrosis factor alpha-dependent proinflammatory gene induction is inhibited by cyclic tensile strain in articular chondrocytes in vitro. Arthritis Rheum 44(10):2311-9, 2001.
Madhavan S, Anghelina M, Rath-Deschner B, Wypasek E, John A, Deschner J, Piesco N, Agarwal S. Biomechanical signals exert sustained attenuation of proinflammatory gene induction in articular chondrocytes. Osteoarthritis Cartilage 14(10):1023-32, 2006.
Marques MR, Hajjar D, Franchini KG, Moriscot AS, Santos MF. Mandibular appliance modulates condylar growth through integrins. J Dent Res 87(2):153-158, 2008.
Matsukawa M, Fukuda K, Yamasaki K, Yoshida K, Munakata H, Hamanishi C. Enhancement of nitric oxide and proteoglycan synthesis due to cyclic tensile strain loaded on chondrocytes attached to fibronectin. Inflamm Res 53(6):239-44, 2004.
Matsushita T, Fukuda K, Yamamoto H, Yamazaki K, Tomiyama T, Oh M, Hamanishi C. Effect of ebselen, a scavenger of reactive oxygen species, on chondrocyte metabolism. Mod Rheumatol 14(1):25-30, 2004.
Nishida K, Doi H, Shimizu A, Yorimitsu M, Takigawa M, Inoue H. The role of IL-4 in the control of mechanical stress-induced inflammatory mediators by rat chondrocytes [abstract]. Arthritis Res Ther 5(Suppl 3):57, 2003.
Rath B, Springorum HR, Deschner J, Luring C, Tingart M, Grifka J, Schaumburger J, Grassel S. Regulation of gene expression in articular cells is influenced by biomechanical loading. Central European Journal of Medicine 2012, doi: 10.2478/s11536-012-0008-x.
Shelton JC, Bader DL, Lee DA. Mechanical conditioning influences the metabolic response of cell-seeded constructs. Cells Tissues Organs 175(3):140-150, 2003.
Shimizu A, Watanabe S, Iimoto S, Yamamoto H. Interleukin-4 protects matrix synthesis in chondrocytes under excessive mechanical stress in vitro. Modern Rheumatology 14(4):296-300, 2004.
Su SC, Tanimoto K, Tanne Y, Kunimatsu R, Hirose N, Mitsuyoshi T, Okamoto Y, Tanne K. Celecoxib exerts protective effects on extracellular matrix metabolism of mandibular condylar chondrocytes under excessive mechanical stress. Osteoarthritis Cartilage 22(6):845-51, 2014.
Tanaka S, Hamanishi C, Kikuchi H, Fukuda K. Factors related to degradation of articular cartilage in osteoarthritis: a review. Semin Arthritis Rheum 27(6):392-399, 1998.
Thomas RS, Clarke AR, Duance VC, Blain EJ. Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis. Arthritis Res Ther 13(6):R203, 2011.
Thompson CL, Chapple JP, Knight MM. Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes. Osteoarthritis Cartilage 22(3):490-8, 2014.
Xu HG, Zhang XH, Wang H, Liu P, Wang LT, Zuo CJ, Tong WX, Zhang XL. Intermittent cyclic mechanical tension-induced calcification and downregulation of ankh gene expression of end plate chondrocytes. Spine (Phila Pa 1976) 37(14):1192-1197, 2012.
Xu HG, Zheng Q, Song JX, Li J, Wang H, Liu P, Wang J, Wang CD, Zhang XL. Intermittent cyclic mechanical tension promotes endplate cartilage degeneration via canonical Wnt signaling pathway and E-cadherin/β-catenin complex cross-talk. Osteoarthritis Cartilage 24(1):158-68, 2016.
Yamazaki K, Fukuda K, Matsukawa M, Hara F, Matsushita T, Yamamoto N, Yoshida K, Munakata H, Hamanishi C. Cyclic tensile stretch loaded on bovine chondrocytes causes depolymerization of hyaluronan: involvement of reactive oxygen species. Arthritis Rheum 48(11):3151-3158, 2003.
Yan L, Zhao L, Li S, Habibou Z. Effects of hedgehog pathway genes on the response to tensile force and inflammatory cytokines in rat condylar cartilage cells. Int J Clin Exp Pathol 9(8):7793-7799, 2016.
Agarwal S, Long P, Gassner R, Piesco NP, Buckley MJ. Cyclic tensile strain suppresses catabolic effects of interleukin-1beta in fibrochondrocytes from the temporomandibular joint. Arthritis Rheum 44(3):608-617, 2001.
Chano T, Tanaka M, Hukuda S, Saeki Y. Mechanical stress induces the expression of high molecular mass heat shock protein in human chondrocytic cell line CS-OKB. Osteoarthritis Cartilage 8(2):115-119, 2000.
Chu F, Feng Q, Hu Z, Shen G. Appropriate cyclic tensile strain promotes biological changes of cranial base synchondrosis chondrocytes. Orthod Craniofac Res 20(3):177-182, 2017.
Deschner J, Rath-Deschner B, Agarwal S. Regulation of matrix metalloproteinase expression by dynamic tensile strain in rat fibrochondrocytes. Osteoarthritis Cartilage 14(3):264-272, 2006.
Deschner J, Rath-Deschner B, Wypasek E, Anghelina M, Sjostrom D, Agarwal S. Biomechanical strain regulates TNFR2 but not TNFR1 in TMJ cells. J Biomech 40(7):1541-1549, 2007.
Madhavan S, Anghelina M, Sjostrom D, Dossumbekova A, Guttridge DC, Agarwal S. Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes. J Immunol 179(9):6246-6254, 2007.
Ohno S, Tanaka N, Ueki M, Honda K, Tanimoto K, Yoneno K, Ohno-Nakahara M, Fujimoto K, Kato Y, Tanne K. Mechanical regulation of terminal chondrocyte differentiation via RGD-CAP/beta ig-h3 induced by TGF-beta. Connect Tissue Res 46(4-5):227-234, 2005.
Rath B, Springorum HR, Deschner J, Luring C, Tingart M, Grifka J, Schaumburger J, Grassel S. Regulation of gene expression in articular cells is influenced by biomechanicalloading. Central European Journal of Medicine 2012, doi: 10.2478/s11536-012-0008-x.
Ru-song Z, Zhu-li Y, Yan-xiao D, Chong-ying Y, Ping-ping J, Xiao Y. Effect of tensile stress on type II collagen and aggrecan expression in rat condylar chondrocytes. Chinese Journal of Tissue Engineering Research 16(20):3649-3653, 2012.
Steinecker-Frohnwieser B, Kaltenegger H, Weigl L, Mann A, Kullich W, Leithner A, Lohberger B. Pharmacological treatment with diacerein combined with mechanical stimulation affects the expression of growth factors in human chondrocytes. Biochemistry and Biophysics Reports 11:154-160, 2017.
Tanaka N, Ohno S, Honda K, Tanimoto K, Doi T, Ohno-Nakahara M, Tafolla E, Kapila S, Tanne K. Cyclic mechanical strain regulates the PTHrP expression in cultured chondrocytes via activation of the Ca2+ channel. J Dent Res 84(1):64-68, 2005.
Tanimoto K, Kamiya T, Tanne Y, Kunimatsu R, Mitsuyoshi T, Tanaka E, Tanne K. Superficial zone protein affects boundary lubrication on the surface of mandibular condylar cartilage. Cell Tissue Res 344(2):333-340, 2011.
Ueki M, Tanaka N, Tanimoto K, Nishio C, Honda K, Lin YY, Tanne Y, Ohkuma S, Kamiya T, Tanaka E, Tanne K. The effect of mechanical loading on the metabolism of growth plate chondrocytes. Ann Biomed Eng 36(5):793-800, 2008.
Xu H, Zhang X, Wang H, Zhang Y, Shi Y, Zhang X. Continuous cyclic mechanical tension increases ank expression in endplate chondrocytes through the TGF-β1 and p38 pathway. Eur J Histochem 57(3):e28, 2013.