Patents & Trademarks


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Flexcell® systems, devices, and consumable products are protected by one or more of the following U.S. or International patents:

  • U.S. Patent 4,789,601 and 4,822,741 (International Patents DE3855631D1, DE3855631T2, EP0365536B1)
    Banes AJ. Biocompatible polyorganosiloxane composition for cell culture apparatus.
  • U.S. Patent 4,839,280
    Banes AJ. Apparatus for applying stress to cell cultures.
  • U.S. Patent 5,122,470
    Banes AJ. Floating cell culture device and method.
  • U.S. Patent 5,518,909
    Banes AJ. Flexion enhanced transfection of genetic material.
  • U.S. Patent 5,593,891
    Banes AJ. Culture plate with splash guard.

  • U.S. Patent 6,037,141
    Banes AJ. Culture compression device.
  • U.S. Patent 6,048,723
    Banes AJ. Flexible bottom culture plate for applying mechanical load to cell cultures.
  • U.S. Patent 6,218,178
    Banes AJ. Loading station assembly.
  • U.S. Patent 6,472,202
    Banes AJ. Loading station assembly and method for tissue engineering.
  • U.S. Patent 6,586,235
    Banes AJ. Apparatus for growing cells in culture under shear stress and/or strain.

  • U.S. Patent 6,645,759
    Banes AJ. Apparatus for growing cells in culture under shear stress and/or strain.
  • U.S. Patent 6,721,667
    Banes AJ, Maloney MM. Method and system for measuring properties of deformable material specimens.
  • U.S. Patent 6,998,265 (International Patents CA2411524C, DE60132626D1, DE60132626T2, EP1356022B1)
    Banes AJ. Method and apparatus to grow and mechanically condition cell cultures.
  • U.S. Patent No. 7,531,624 and 8,288,511
    Banes AJ, Qi J. Nuclear targeting sequence.
  • U.S. Patent No. 7,738,682
    Banes AJ, Maloney M. Tissue engineered construct analytical imaging system and method of obtaining and analyzing images of tissue engineered constructs.

  • U.S. Patent No. 8,663,988; 8,877,500; 8,993,325, and 9,018,009
    Banes AJ, Tsuzaki M, Qi J. Thermally induced gelation of collagen hydrogel and method of thermally inducing gelling a collagen hydrogel.
  • U.S. Patent D694,904
    Banes AJ, Frazier C, Wimmer C. Three well culture plate.

  • U.S. Patent Publication No. US20060134779A1 (International Patent WO2005023988A2)
    Banes AJ, Ji Q. Modulation of cell intrinsic strain to control cell modulus, matrix synthesis, secretion, organization, material properties and remodeling of tissue engineered constructs.
  • U.S. Patent Publication No. US20090123993A1
    Banes AJ, Wang J, Qi J, Kheradpir K. Bioreactor for development of blood vessels.
  • U.S. Patent Publication No. US20100041128A1
    Banes AJ, Wang J, Wall ME. Microfluidic device for application of shear stress and tensile strain.
  • U.S. Patent Publication No. US20130337565 A11
    Banes AJ, Frazier C, Wimmer C. Method and apparatus for patterning cells .


The following names are registered trademarks of Flexcell® International Corp. or Medtrain Technologies, LLC:

  • Flexcell®
  • BioFlex®
  • Tissue Train®
  • Osci-Flow®
  • Streamer®
  • Cutlure Slips®
  • Arctangle®
  • Collagel®
  • FlexLink®
  • StageFlexer®
  • UniFlex®
  • Thermacol®
  • HiQ Flowmate®
  • Flexercell®