As we enter week 5 of Coronavirus confinement, the reality that the world has changed not only rings in my ears from multiple news outlets, but is also seen in plain sight across our communities. As we have done during past global crises, we must again do now…ADAPT! Speaking of adaptation, that is exactly what viruses do best! Viruses are described as neither living nor dead particles that have a parasitic-like relationship with the living cells it needs to thrive. Scientists are helping to explain what, where and how the novel 2019 Coronavirus has become one of the deadliest pandemics in the last century. As I write this blog, promising research is being done on antibodies that may give guidance on how to neutralize it. We know the COVID19 attacks the respiratory system, specifically the lungs, as well as, other vital organs. Other studies performed in the field of Pulmonary research, where Flexcell® Tension Systems are being used to understand lung cell signaling inflammatory responses, gene expression and mRNA response to mechanical stretch, alveloar macrophage biomarkers, cytokine protein expression and ventilator-induced lung injury. Flexcell® is looking for scientific collaborators interested in Pulmonary research areas utilizing our cell-stretching bioreactor technology. Please contact our team at [email protected] to learn more about our products and how we may be able to help support your research needs!
According to the Chinese Zodiac solar calendar, this is the year of the Rat, which signifies vitality, success and cleverness. The Chinese Lunar New Year is also called the Spring Festival (春节—chūn jié) and it lasts from January 25th - February 4th, 2020. Each day has a specific meaning, tradition and food that is celebrated with family and friends. As with each New Year, we tend to start with many resolutions, goals and future plans. In 2020, scientific discovery will continue to focus on ways to expand our knowledge of the human genome, how to eliminate disease and repair the body through regenerative medicine. In the near future, Artificial Intelligence will help human scientific explorers analyze, perform and build on new unforeseen technologies. Projects that focus on building and sequencing genomics are being used, even in the last few weeks, to create models for understanding virus outbreaks, like the Wuhan Coronavirus. Stem cell researchers are getting closer to the reality of producing human replacement organoids in vitro. These discoveries will have huge implications on organ donation, surgical treatment and wound healing for patients. We are living in an interesting time where science, information technology, new biomaterials and medicine have collided, which will bring humanity new therapeutic solutions. Our company mission is to be an enabler of technology to help research investigators continue with their scientific discoveries.
Thank you to everyone who stopped by Flexcell's booth at ASCB 2019 where we introduced our new Cell Soft™ Soft Substrate Culture Ware! With CellSoft™, Flexcell® has created even softer substrates to match the material properties of tissue niches and better meet the needs of biological laboratories wanting to grow their cells on native stiffness substrates. CellSoft™ comes in various stiffnesses (moduli range 1-80 kPa), and plate formats (round dishes and multi-well plates). It is available covalently bonded with Collagen I or other matrices, pre-sterilized and ready to use. CellSoft™ BioFlex™ culture plates are the only commercially viable product to grow cells on a soft substrate and stretch your cells with the FX-6000™ Tension System.
In this study, human ADSCs (hADSCs) were applied cyclic stretch stimulation under an in vitro stretching model for designated duration. We found that mechanical stretch significantly promoted the proliferation, adhesion and migration of hADSCs, suppressing cellular apoptosis and increasing the production of pro‐healing cytokines.
Burlington’s Flexcell has manufactured scientific products for testing cell-level biochemical reactions since 1987.Flexcell products have medical applications across fields like orthopedics, cardiovascular medicine, pulmonary health, and tissue engineering research.
The Biotechnology Department at Alamance Community College (ACC) shows no signs of slowing down its historic push to provide students with the latest cutting-edge training in new technologies that have long paved the way for career opportunities in the biomanufacturing industry.