Publications Searchable Database

Wang X, Tao J, Zhou J, Shu Y, Xu J. Excessive load promotes temporomandibular joint chondrocyte apoptosis via Piezo1/endoplasmic reticulum stress pathway. J Cell Mol Med. 2024; 28:e18472. doi:10.1111/jcmm.18472

Shaver, M., Gomez, K., Kaiser, K. et al. Mechanical stretch leads to increased caveolin-1 content and mineralization potential in extracellular vesicles from vascular smooth muscle cells. BMC Mol and Cell Biol 25, 8 (2024). https://doi.org/10.1186/s12860-024-00504-w

Diagbouga, Mannekomba R., et al. "Impact of disrupted cyclic stretch in intracranial aneurysms: Insights from endothelial cell transcriptomic dataset." Data in Brief 52 (2024): 110014.

Warwar, Rachel, et al. "Uterine fibroid cell cytoskeletal organization is affected by altered G protein-coupled estrogen receptor-1 and phosphatidylinositol 3-kinase signaling." F&S Science 4.4 (2023): 327-338.

Chen, Y., et al. "Occlusal force maintains alveolar bone homeostasis via type H angiogenesis." Journal of Dental Research 102.12 (2023): 1356-1365.

Chen Y, Luo M, Xie Y, Xing L, Han X...Periodontal ligament-associated protein-1 engages in teeth overeruption and periodontal fiber disorder following occlusal hypofunction, Journal of Periodontal Research, 2023.

Ren X, Zhuang H, Li B, Zhang Y…Gsmtx4 Alleviated Osteoarthritis through Piezo1/Calcineurin/NFAT1 Signaling Axis under Excessive Mechanical Strain, Int. J. Mol. Sci. 2023.

Uzieliene I, Bironaite D, Pachaleva J, Bagdonas E, Sobolev A, Tsai W-B, Kvedaras G, Bernotiene E. Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair. International Journal of Molecular Sciences, 24(4):3451, 2023.

Liu M, Samany S, Vasa CH, Pedrigi RM, Oguz UM…, Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis. Plos One, 2023.

Xu, F., Li, S., Wang, S., Yuan, M., Zheng, S., Liu, C., … & Sun, H. (2023). Piezo1 mediates the degradation of cartilage extracellular matrix in malocclusion‐induced tmjoa. Oral Diseases, 30(4), 2425-2438. https://doi.org/10.1111/odi.14615

Sheng, Xin, et al. "Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs." Cell and Tissue Research (2022): 1-15.

Dong, Lili, et al. "Mechanical stretch induces osteogenesis through the alternative activation of macrophages." Journal of Cellular Physiology 236.9 (2021): 6376-6390.

Halle, Jessica L., et al. "The effect of mechanical stretch on myotube growth suppression by colon-26 tumor-derived factors." Frontiers in Cell and Developmental Biology 9 (2021): 690452.

Ge, Yuxiang, et al. "Effects of mechanical compression on chondrogenesis of human synovium-derived mesenchymal stem cells in agarose hydrogel." Frontiers in bioengineering and biotechnology 9 (2021): 697281.

Yu, Huan, et al. "Osteopontin activates retinal microglia causing retinal ganglion cells loss via p38 MAPK signaling pathway in glaucoma." The FASEB Journal 35.3 (2021): e21405.

Cardona-Ramirez, Sebastian, et al. "Fibroblasts from common anterior cruciate ligament tendon grafts exhibit different biologic responses to mechanical strain." The American Journal of Sports Medicine 49.1 (2021): 215-225.

Riehl, Brandon D., et al. "The role of fluid shear and metastatic potential in breast cancer cell migration." Journal of Biomechanical Engineering 142.10 (2020): 101001.

Kreutzer, Joose, et al. "Pneumatic unidirectional cell stretching device for mechanobiological studies of cardiomyocytes." Biomechanics and Modeling in Mechanobiology 19 (2020): 291-303.

Fujiwara, Yuya, et al. "A Method for Contraction Force Measurement of hiPSC-Derived Engineered Cardiac Tissues." Pluripotent Stem-Cell Derived Cardiomyocytes (2021): 171-180.

Ilze Donderwinkel, Rocky S. Tuan, Neil R. Cameron, Jessica E. Frith, A systematic investigation of the effects of TGF-β3 and mechanical stimulation on tenogenic differentiation of mesenchymal stromal cells in a poly(ethylene glycol)/gelatin-based hydrogel, Journal of Orthopaedic Translation, Volume 43, 2023, https://doi.org/10.1016/j.jot.2023.09.006.

Sooranna SR, Lee Y, Kim LU, Mohan AR, Bennett PR, Johnson MR. Mechanical stretch activates type 2 cyclooxygenase via activator protein-1 transcription factor in human myometrial cells. Mol Hum Reprod 10(2):109-113, 2004.

Takemura M, Itoh H, Sagawa N, Yura S, Korita D, Kakui K, Hirota N, Fujii S. Cyclic mechanical stretch augments both interleukin-8 and monocyte chemotactic protein-3 production in the cultured human uterine cervical fibroblast cells. Mol Hum Reprod 10(8):573-580, 2004.

Korita D, Sagawa N, Itoh H, Yura S, Yoshida M, Kakui K, Takemura M, Yokoyama C, Tanabe T, Fujii S. Cyclic mechanical stretch augments prostacyclin production in cultured human uterine myometrial cells from pregnant women: possible involvement of up-regulation of prostacyclin synthase expression. J Clin Endocrinol Metab 87(11):5209-5219, 2002.

Korita D, Itoh H, Sagawa N, Yura S, Yoshida M, Kakui K, Takemura M, Nuamah MA, Fujii S. Cyclic mechanical stretching and interleukin-1alpha synergistically up-regulate prostacyclin secretion in cultured human uterine myometrial cells. Gynecol Endocrinol 18(3):130-7, 2004.

Mohan AR, Sooranna SR, Lindstrom TM, Johnson MR, Bennett PR. The effect of mechanical stretch on cyclooxygenase type 2 expression and activator protein-1 and nuclear factor-kappaB activity in human amnion cells. Endocrinology 148(4):1850-1857, 2007.

Yoshida M, Sagawa N, Itoh H, Yura S, Takemura M, Wada Y, Sato T, Ito A, Fujii S. Prostaglandin F(2alpha), cytokines and cyclic mechanical stretch augment matrix metalloproteinase-1 secretion from cultured human uterine cervical fibroblast cells. Mol Hum Reprod 8(7):681-687, 2002.

Taylor SE, Vaughan-Thomas A, Clements DN, Pinchbeck G, Macrory LC, Smith RK, Clegg PD. Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems. BMC Musculoskelet Disord 10:27, 2009.

Tondon A, Haase C, Kaunas R. Mechanical stretch assays in cell culture systems. In: Handbook of Imaging in Biological Mechanics, ed. Neu CP, Genin GM. CRC Press: Boca Raton, 2015.

Vande Geest JP, Di Martino ES, Vorp DA. An analysis of the complete strain field within FlexercellTM membranes. Journal of Biomechanics 37:1923-1928, 2004.

Wilson CJ, Kasper G, Schütz MA, Duda GN. Cyclic strain disrupts endothelial network formation on Matrigel. Microvasc Res 78(3):358-63, 2009

de Lange WJ, Grimes AC, Hegge LF, Ralphe JC. Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue. J Gen Physiol 141(1):73-84, 2013.

Jones BF, Wall ME, Carroll RL, Washburn S, Banes AJ. Ligament cells stretch-adapted on a microgrooved substrate increase intercellular communication in response to a mechanical stimulus. J Biomech 38(8):16531664, 2005.

de Jonge N, Foolen J, Brugmans MC, Söntjens SH, Baaijens FP, Bouten CV. Degree of scaffold degradation influences collagen (re)orientation in engineered tissues. Tissue Eng Part A 20(11-12):1747-57, 2014.

Takemura M, Itoh H, Sagawa N, Yura S, Korita D, Kakui K, Kawamura M, Hirota N, Maeda H, Fujii S. Cyclic mechanical stretch augments hyaluronan production in cultured human uterine cervical fibroblast cells. Mol Hum Reprod 11(9):659-665, 2005.

Sooranna SR, Engineer N, Loudon JA, Terzidou V, Bennett PR, Johnson MR. The mitogen-activated protein kinase dependent expression of prostaglandin H synthase-2 and interleukin-8 messenger ribonucleic acid by myometrial cells: the differential effect of stretch and interleukin-1beta. J Clin Endocrinol Metab 90(6):3517-3527, 2005.

Ahearne M, Bagnaninchi PO, Yang Y, El Haj AJ. Online monitoring of collagen fibre alignment in tissueengineered tendon by PSOCT. J Tissue Eng Regen Med 2(8):521-524, 2008.

‍Chin-Smith EC, Willey FR, Slater DM, Taggart MJ, Tribe RM. Nuclear factor of activated T-cell isoform expression and regulation in human myometrium. Reprod Biol Endocrinol 13:83, 2015.

Nourse MB, Halpin DE, Scatena M, Mortisen DJ, Tulloch NL, Hauch KD, Torok-Storb B, Ratner BD, Pabon L, Murry CE. VEGF induces differentiation of functional endothelium from human embryonic stem cells: implications for tissue engineering. Arterioscler Thromb Vasc Biol 30(1):80-89, 2010.

Lee CH, Shin HJ, Cho IH, Kang YM, Kim IA, Park KD, Shin JW. Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. Biomaterials 26(11):1261-1270, 2005.

Masumoto H, Nakane T, Tinney JP, Yuan F, Ye F, Kowalski WJ, Minakata K, Sakata R, Yamashita JK, Keller BB. The myocardial regenerative potential of three-dimensional engineered cardiac tissues composed of multiple human iPS cell-derived cardiovascular cell lineages. Sci Rep 6:29933, 2016.

Gilbert JA, Weinhold PS, Banes AJ, Link GW, Jones GL. Strain profiles for circular cell culture plates containing flexible surfaces employed to mechanically deform cells in vitro. Journal of Biomechanics 27(9):1169-1177, 1994.

Clause KC, Tinney JP, Liu LJ, Gharaibeh B, Huard J, Kirk JA, Shroff SG, Fujimoto KL, Wagner WR, Ralphe JC, Keller BB, Tobita K. A three-dimensional gel bioreactor for assessment of cardiomyocyte induction in skeletal muscle-derived stem cells. Tissue Eng Part C Methods 16(3):375-385, 2010.

Brown TD, Bottlang M, Pedersen DR, Banes AJ. Loading paradigms--intentional and unintentional--for cell culture mechanostimulus. Am J Med Sci 316(3):162-168, 1998.

Brown TD, Bottlang M, Pedersen DR, Banes AJ. Development and experimental validation of a fluid/structure-interaction finite element model of a vacuum-driven cell culture mechanostimulus system. Comput Methods Biomech Biomed Engin 3(1):65-78, 2000.

Yang Y, Wimpenny I, Wang RK. Application of polarization-sensitive OCT and Doppler OCT in tissue engineering. In: Optical Techniques in Regnerative Medicine, Edited by Morgan SP, Rose F, Matcher SJ. Taylor & Francis Group: Florida, p. 307-327, 2014.

Matheson LA, Jack FN, Maksym GN, Paul SJ, Labow RS. Characterization of the Flexcell Uniflex cyclic strain culture system with U937 macrophage-like cells. Biomaterials 27(2):226-233, 2006.

Abraham T, Kayra D, McManus B, Scott A. Quantitative assessment of forward and backward second harmonic three dimensional images of collagen type I matrix remodeling in a stimulated cellular environment. J Struct Biol 180(1):17-25, 2012.

Colombo A, Cahill PA, Lally C. An analysis of the strain field in biaxial Flexcell membranes for different waveforms and frequencies. Proc Inst Mech Eng H 222(8):1235-1245, 2008.

Clause KC, Tinney JP, Liu JL, Keller BB, Huard J, Tobita K. p38MAP-kinase regulates cardiomyocyte proliferation and contractile properties of engineered early embryonic cardiac tissue [abstract]. Weinstein Cardiovascular Development Research Conference, Indianapolis, IN, 2007.

Wall ME, Otey C, Qi J, Banes AJ. Connexin 43 is localized with actin in tenocytes. Cell Motil Cytoskeleton 64(2):121-130, 2007.

Tsuzaki M, Bynum D, Almekinders L, Yang X, Faber J, Banes AJ. ATP modulates load-inducible IL-1, COX 2, and MMP-3 gene expression in human tendon cells. J Cell Biochem 89(3):556-562, 2003.

Qi J, Chi L, Bynum D, Banes AJ. Gap junctions in IL-1β-mediated cell survival response to strain. J Appl Physiol 110(5):1425-1431, 2011.

Jones E, Legerlotz K, Riley G. Mechanical regulation of integrins in human tenocytes in collagen and fibrin matrices. Bone Joint J 96-B(Supp 11):161, 2014.

Tsuzaki M, Bynum D, Almekinders L, Faber J, Banes AJ. Mechanical loading stimulates ecto-ATPase activity in human tendon cells. J Cell Biochem 96(1):117-125, 2003.

Ralphs JR, Waggett AD, Benjamin M. Actin stress fibres and cell-cell adhesion molecules in tendons: organisation in vivo and response to mechanical loading of tendon cells in vitro. Matrix Biology 21(1):67-74, 2002.

Qi J, Chi L, Maloney M, Yang X, Bynum D, Banes AJ. Interleukin-1beta increases elasticity of human bioartificial tendons. Tissue Eng 12(10):2913-2925, 2006.

Backman LJ, Fong G, Andersson G, Scott A, Danielson P. Substance P is a mechanoresponsive, autocrine regulator of human tenocyte proliferation. PLoS One 6(11):e27209, 2011.

Momberger TS, Levick JR, Mason RM. Hyaluronan secretion by synoviocytes is mechanosensitive. Matrix Biology 24(8):510-519, 2005.

Mousavizadeh R, Backman L, McCormack RG, Scott A. Dexamethasone decreases substance P expression in human tendon cells: an in vitro study. Rheumatology (Oxford) 54(2):318-23, 2015.

Mousavizadeh R, Khosravi S, Behzad H, McCormack RG, Duronio V, Scott A. Cyclic strain alters the expression and release of angiogenic factors by human tendon cells. PLoS One 9(5):e97356, 2014.

Kayama T, Mori M, Ito Y, Matsushima T, Nakamichi R, Suzuki H, Ichinose S, Saito M, Marumo K, Asahara H. Gtf2ird1-dependent Mohawk expression regulates mechanosensing properties of the tendon. Mol Cell Biol 36(8):1297-309, 2016.

Spang C, Backman LJ, Le Roux S, Chen J, Danielson. Glutamate signaling through the NMDA receptor reduces the expression of scleraxis in plantaris tendon derived cells. BMC Musculoskelet Disord 18(1):218, 2017.

Wall ME, Weinhold PS, Siu T, Brown TD, Banes AJ. Comparison of cellular strain with applied substrate strain in vitro. J Biomech 40(1):173-181, 2007.

Lohberger B, Kaltenegger H, Stuendl N, Rinner B, Leithner A, Sadoghi P. Impact of cyclic mechanical stimulation on the expression of extracellular matrix proteins in human primary rotator cuff fibroblasts. Knee Surg Sports Traumatol Arthrosc 24(12):3884-3891, 2016.

Triantafillopoulos IK, Banes AJ, Elfervig MK, Garrett WE, Karas SG. Nandrolone decanoate and loading enhance intercellular calcium signalling in human supraspinatus tendon cells [abstract]. J Bone Joint Surg Br Orthopaedic Proceedings 86-B:171, 2004.

Lavagnino M, Gardner KL, Arnoczky SP. High magnitude, in vitro, biaxial, cyclic tensile strain induces actin depolymerization in tendon cells. Muscles Ligaments Tendons J 5(2):124-8, 2015.

Wall ME, Banes AJ. Mechanically-induced strain upregulates connexin-43 mRNA expression in tendon cells [abstract]. Transactions of the 50th Annual Meeting of the Orthopaedic Research Society 29:827, 2004.

Qi J, Fox AM, Alexopoulos LG, Chi L, Bynum D, Guilak F, Banes AJ. IL-1beta decreases the elastic modulus of human tenocytes. J Appl Physiol 101(1):189-95, 2006.

Triantafillopoulos IK, Banes AJ, Bowman KF Jr, Maloney M, Garrett WE Jr, Karas SG. Nandrolone decanoate and load increase remodeling and strength in human supraspinatus bioartificial tendons. Am J Sports Med 32(4):934-943, 2004.

Jones ER, Jones GC, Legerlotz K, Riley GP. Cyclical strain modulates metalloprotease and matrix gene expression in human tenocytes via activation of TGFβ. Biochim Biophys Acta 1833(12):2596-2607, 2013.

Chen G, Jiang H, Tian X, Tang J, Bai X, Zhang Z, Wang L. Mechanical loading modulates heterotopic ossification in calcific tendinopathy through the mTORC1 signaling pathway. Mol Med Rep 16(5):5901-5907, 2017. doi: 10.3892/mmr.2017.7380.

Chen CH, Marymont JV, Huang MH, Geyer M, Luo ZP, Liu X. Mechanical strain promotes fibroblast gene expression in presence of corticosteroid. Connect Tissue Res 48(2):65-9, 2007.

Banes AJ, Weinhold P, Yang X, Tsuzaki M, Bynum D, Bottlang M, Brown T. Gap junctions regulate responses of tendon cells ex vivo to mechanical loading. Clin Orthop Relat Res 367 Suppl:S356-S370, 1999.

Elfervig M, Archambault J, Herzog W, Bynum D, Banes AJ. Mechanical stretching induces increased intracellular Ca2+ in human tendon cells [abstract]. Transactions of the 47th Annual Meeting of the Orthopaedic Research Society 26:566, 2001.

Huisman E, Lu A, McCormack R, Scott A. Enhanced collagen type I synthesis of tenocytes by periodic in vitro mechanical stimulation. Br J Sports Med 48:A28, 2014.

Gilbert JA, Weinhold PS, Banes AJ, Link GW, Jones GL. Strain profiles for circular cell culture plates containing flexible surfaces employed to mechanically deform cells in vitro. Journal of Biomechanics 27(9):1169-1177, 1994.

Garvin J, Qi J, Maloney M, Banes AJ. Novel system for engineering bioartificial tendons and application of mechanical load. Tissue Eng 9(5):967-979, 2003.

Hirata H, Nagakura T, Tsujii M, Morita A, Fujisawa K, Uchida A. The relationship of VEGF and PGE2 expression to extracellular matrix remodelling of the tenosynovium in the carpal tunnel syndrome. J Pathol 204(5):605-612, 2004.

Fong G, Backman LJ, Hart DA, Danielson P, McCormack B, Scott A. Substance P enhances collagen remodeling and MMP-3 expression by human tenocytes. J Orthop Res 31(1):91-8, 2013.

Cao TV, Hicks MR, Campbell D, Standley PR. Dosed myofascial release in three-dimensional bioengineered tendons: effects on human fibroblast hyperplasia, hypertrophy, and cytokine secretion. J Manipulative Physiol Ther 36(8):513-21, 2013.

Cao TV, Hicks MR, Zein-Hammoud M, Standley PR. Duration and magnitude of myofascial release in 3-dimensional bioengineered tendons: effects on wound healing. J Am Osteopath Assoc 115(2):72-82, 2015.

Huisman E, Lu A, McCormack RG, Scott A. Enhanced collagen type I synthesis by human tenocytes subjected to periodic in vitro mechanical stimulation. BMC Musculoskelet Disord 15:386, 2014.

Momberger TS, Levick JR, Mason RM. Mechanosensitive synoviocytes: a Ca2+ -PKC-MAP kinase pathway contributes to stretch-induced hyaluronan synthesis in vitro. Matrix Biol 25(5):306-316, 2006.

Thaler JD, Achari Y, Lu T, Shrive NG, Hart DA. Estrogen receptor beta and truncated variants enhance the expression of transfected MMP-1 promoter constructs in response to specific mechanical loading. Biology of Sex Differences 5:14, 2014.

Sambajon VV, Cillo JE, Gassner RJ, Buckley MJ. The effects of mechanical strain on synovial fibroblasts. Journal of Oral and Maxillofacial Surgery 61(6):707-712, 2003.

Almekinders LC, Banes AJ, Ballenger CA. Effects of repetitive motion on human fibroblasts. Med Sci Sports Exerc 25(5):603-607, 1993.

Bader RA, Wagoner KL. Modulation of the response of rheumatoid arthritis synovial fibroblasts to proinflammatory stimulants with cyclic tensile strain. Cytokine 51(1):35-41, 2010.

Archambault J, Tsuzaki M, Herzog W, Banes AJ. Stretch and interleukin-1beta induce matrix metalloproteinases in rabbit tendon cells in vitro. Journal of Orthopaedic Research 20(1):36-39, 2002.

Lange F, Hartl S, Ungethuem U, Kuban RJ, Hammerschmidt S, Faber S, Morawietz L, Wirtz H, Emmrich F, Krenn V, Sack U. Anti-TNF effects on destructive fibroblasts depend on mechanical stress. Scand J Immunol 64(5):544-553, 2006.

Andersson G, Backman L. 13 Fibrotic regulators Ccn1 and Ccn2 respond to mechanical loading of tendon cells. Br J Sports Med 48:A8-A9, 2014.

Yu HC, Wu TC, Chen MR, Liu SW, Chen JH, Lin KM. Mechanical stretching induces osteoprotegerin in differentiating C2C12 precursor cells through noncanonical Wnt pathways. J Bone Miner Res 25(5):1128-1137, 2010.

Yang G, Rothrauff BB, Lin H, Gottardi R, Alexander PG, Tuan RS. Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix. Biomaterials 34(37):9295-306, 2013.

Tsujii M, Hirata H, Yoshida T, Imanaka-Yoshida K, Morita A, Uchida A. Involvement of tenascin-C and PG-M/versican in flexor tenosynovial pathology of idiopathic carpal tunnel syndrome. Histol Histopathol 21(5):511-518, 2006.

Banes AJ, Gilbert J, Taylor D, Monbureau O. A new vacuum-operated stress-providing instrument that applies static or variable duration cyclic tension or compression to cells in vitro. J Cell Sci 75:35-42, 1985.

Banes AJ, Tsuzaki M, Peiqi H, Brigman B, Brown T, Almekinders L, Lawrence WT, Fischer T. PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro. Journal of Biomechanics 28(12):1505-1513, 1995.

Arnoczky SP, Tian T, Lavagnino M, Gardner K, Schuler P, Morse P. Activation of stress-activated protein kinases (SAPK) in tendon cells following cyclic strain: the effects of strain frequency, strain magnitude, and cytosolic calcium. Journal of Orthopaedic Research 20(5):947-952, 2002.

Banes AJ, Tsuzaki M, Lawrence WT, Ralphs J, Benjamin M, Pederson D, Brown T. Gap junction connexin expression is upregulated by cyclic mechanical load in avian tendon cells. Biorheology 32(2):177, 1995.

Banes AJ, Horesovsky G, Larson C, Tsuzaki M, Judex S, Archambault J, Zernicke R, Herzog W, Kelley S, Miller L. Mechanical load stimulates expression of novel genes in vivo and in vitro in avian flexor tendon cells. Osteoarthritis Cartilage 7(1):141-153, 1999.

Simionescu A, Tedder ME, Chuang T, Simionescu DT. Lectin and antibody-based histochemical techniques for cardiovascular tissue engineering. Journal of Histotechnology 34(1):20-28, 2011.

Shi GX, Zheng XF, Zhu C, Li B, Wang YR, Jiang SD, Jiang LS. Evidence of the role of R-spondin 1 and its receptor Lgr4 in the transmission of mechanical stimuli to biological signals for bone formation. Int J Mol Sci 18(3), 2017. pii: E564.